Endocrine Abstracts

IntroductionNon-functioning pituitary adenomas (NFPA) present approximately 15% to 30% of all pituitary adenomas. They are most commonly misdiagnosed, until they are large enough to lead to mass effect and hypopituitrasm. The present study was carried out with the aim of studying the clinical and biological characteristics of patients who are followed for NFA.Patients and methodsThis is a retrospective study ...

Background: Diabetes mellitus poses a global chronic health challenge, with Tunisia experiencing a concerning surge in type 2 diabetes (T2D) prevalence. Cardiovascular and renal complications are prominent and severe consequences associated with T2D. Evaluating the costs related to managing these complications is crucial to enhance care quality, optimize resource utilization, and ultimately reduce the growing economic and social burden of this chronic disease.<p class="abs...

Introduction: Precocious puberty is characterized by the onset of signs of puberty before the usual age and can be caused by various etiologies. Congenital adrenal hyperplasia represents a rare cause of precocious puberty. Our aim was to report a case of a child with precocious puberty.Observation: A 4-year-old and 11 months patient, from a consanguineous marriage, hospitalized in the endocrinology department for precocious puberty. The clinical examinat...

Introduction: Ketoacidosis is a frequent and life-threatening complication of diabetes. Our aim was to study the Correlation between kalemia and biochemical parameters in patients with diabetic ketoacidosis.Methods: This is a retrospective descriptive study concerning all patients hospitalized in the Endocrinology Department for Diabetic Ketoacidosis (DKA) between August 2021 to December 2022. Acidosis markers were measured using an ABL 80 FLEX blood gas...

Introduction & Objective: Hidradenitis Suppurativa (HS), or Verneuil’s disease, is a chronic suppurative inflammatory condition. This study aims to determinate the association between HS and metabolic diseases.Materials and Methods: We conducted a retrospective study between January 2012 and December 2022 enrolling all cases of HS in our dermatology department.Results: Over 11 years, we collected 77 cases. The average age ...

Introduction: The H syndrome, an autosomal recessive genodermatosis, is characterized by cutaneous and systemic manifestations resulting from mutations in the SLC29A3 gene (10q22.2), leading to histiocytic infiltration of multiple organs. This study presents a new observation of H syndrome.Observation: We report the case of a 33-year-old patient, born of consanguineous parents, with a history of diabetes diagnosed at the age of 28 and treated with oral a...

Background: Diabetes mellitus presents a pervasive global health challenge, and Tunisia grapples with a concerning upswing in the prevalence of type 2 diabetes (T2D). Cardiovascular and renal complications stand out as prevalent and severe outcomes linked to T2D. Evaluating the costs associated with managing these complications in T2D patients is pivotal for improving care quality, optimizing resource allocation, and ultimately mitigating the escalating economic and social bur...

Introduction: Metformin, the primary treatment for type 2 diabetes, is renowned for its positive effects on carbohydrate metabolism, weight management, and vascular health. Despite these well-established benefits, prolonged use of metformin has been linked to potential adverse reactions, including a decrease in serum vitamin B12 levels and the development of anemia1. This case further emphasizes the complexities associated with metformin use by introducing an unusua...

Introduction: Obesity is recognized as a risk factor for cardiovascular diseases. She can be associated with cardio-metabolic diseases. The objective of our study was to determine the metabolic profile of our obese adults.Materials and methods: This is a descriptive cross-sectional study involving obese adults consulting the service of Endocrinology of Sfax, Hedi Chaker University Hospital in 2023.Results: We recruited 40 obese pat...

Introduction: Multiple endocrine neoplasia type 2A (MEN2A) is a rare genetic tumor syndrome due to germline mutations of the RET proto-oncogene, which is characterized by medullary thyroid cancer (MTC), pheochromocytoma, and primary hyperparathyroidism. Our aim was to report a case of a patient with MEN2.Observation: A 45-year-old patient, with a history of diabetes and corticotropic insufficiency, consulted for paresthesias. The biology showed hypercalc...